Is delta-9-tetrahydrocannabinol estrogenic

Chronic cannabis abuse, delta-9-tetrahydrocannabinol and thyroid function.

OBJECTIVE The aim of this study was to obtain rather rare information about the influence of chronic cannabis abuse on thyroid function. METHODS Thyroid function tests (TSH, total T3, free T4) of 39 chronic cannabis-dependent subjects (ICD-10) were determined at admission (for in-patient detoxification). In a subgroup, serum levels of thyroid hormones were correlated with the serum levels of ...

Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.

Evidence for an analgesic interaction between delta-9-tetrahydrocannabinol (Delta(9)-THC) and morphine was sought using an experimental pain model applied to normal volunteers. The study incorporated a double blinded, four treatment, four period, four sequence, crossover design. Subjects received Delta(9)-THC 5 mg orally or placebo and 90 min later morphine 0.02 mg/kg intravenously or placebo. ...

delta 9-Tetrahydrocannabinol reduces brain regional histamine concentrations.

Simplified analysis of 11-hydroxy-delta-9-tetrahydrocannabinol and 11-carboxy-delta-9-tetrahydrocannabinol in human meconium: method development and validation.

We describe the development of a sensitive analytical method for the analysis of 11-hydroxy-delta-9-tetrahydrocannabinol (11-OH-THC) and 11-carboxy-delta-9-tetrahydrocannabinol (THCC) in meconium using a gas chromatography-mass spectrometry (GC/MS) platform. The method was validated according to protocols, which included assessment of accuracy, precision, robustness, stability in meconium and i...

Cannabis – review of the issues related to determination of the total content of delta-9-tetrahydrocannabinol (D-9-THC) and delta 9-tetrahydrocannabinolic acid (D-9-THCA-A)

practices, then in medicine and textile industry, and over the last few decades they have become the world’s most popular and widespread drug drug. The history of cannabis consumption goes back several thousand years when it originated in Asia. The first references to cannabis can be found in Chinese and Indian writings such as Vedian hymns and Indian religious songs, dated back to the first mi...